비아그라 - 개요
비아그라 - 개요
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The suggest steady condition quantity of distribution (Vss) for sildenafil is 105 L, indicating distribution in to the tissues. Sildenafil and its main circulating N-desmethyl metabolite are the two around 96% bound to plasma proteins. Protein binding is independent of total drug concentrations.
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Sufferers who exhibit hemodynamic instability on alpha-blocker therapy by itself are at increased risk of symptomatic hypotension with concomitant use of PDE5 inhibitors. Clients really should be steady on alpha-blocker therapy just before initiating a PDE5 inhibitor.
VIAGRA shouldn't be applied with REVATIO or with other PAH treatment plans that contains sildenafil or another PDE5 inhibitors (for example Adcirca [tadalafil])
Consequences of Other Medicines on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (big route) and CYP2C9 (minor route). For that reason, inhibitors of these isoenzymes may possibly cut down sildenafil clearance and inducers of those isoenzymes may enhance sildenafil clearance.
VIAGRA contains sildenafil, which is identical medication present in An additional drug called REVATIO. REVATIO is made use of to deal with a uncommon sickness identified as pulmonary arterial hypertension (PAH).
VIAGRA could impact how other medicines work, and other medicines could have an affect on the way in which VIAGRA performs, causing Uncomfortable side effects. Especially inform your healthcare supplier if you take any of the following:
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an erection that will not go away (priapism). When 비아그라 구입 you have an erection that lasts greater than 4 several hours, get health care aid immediately. If it is not 비아그라 구입 dealt with instantly, priapism can permanently problems your penis
Medical professionals should alert clients that extended erections better than 4 hours 비아그라 구입 and priapism (distressing erections larger than 6 hours in period) are documented infrequently since sector approval of VIAGRA.
Next, in contrast to our rivals, we promote the true deal. Our sildenafil tablets are available in the actual 25mg, 50mg, and 100mg dosage sizes. We feel that should you’re getting ready for any Particular time using your associate, the concept of getting 5 pills just to get and preserve an erection sounds absurd.
Medical professionals need to take into account no matter whether their individuals with fundamental NAION chance aspects might be adversely afflicted by utilization of PDE5 inhibitors. People who have previously skilled NAION are at amplified threat of NAION recurrence. Hence, PDE5 inhibitors, like VIAGRA, should be utilised with warning in these patients and only once the predicted benefits outweigh the pitfalls.
In several scenarios, clinical comply with-up data was restricted. It's impossible to find out regardless of whether these noted situations are linked directly to using VIAGRA, 정품비아그라구매 for the patient's fundamental risk components for hearing reduction, a mix of these aspects, or to other things [see WARNINGS AND PRECAUTIONS and Client Info].
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